New York: Common drugs used to prevent heart attacks and lower blood pressure may also increase survival rates of people living with melanoma — the most deadly type of skin cancer — a study has found.
Patients with metastatic melanoma, or melanoma that has spread to other parts of the body, often have a poor prognosis, and while some forms of immunotherapy — treatments that boost the body’s immune system to fight disease — are promising, response rates are less than 35 per cent.
The findings showed that melanoma patients who received immunotherapy while taking a specific type of beta blocker lived longer than patients who received immunotherapy alone.
“Beta blockers slow your heart rhythm but they can also affect immune cells and improve immune function,” said Todd Schell, Professor at the Pennsylvania State University.
Pan beta blockers, one of the least prescribed, was found as more effective against melanoma.
The effect is believed to be the result of lower stress levels that beta-blockers provide, the researchers said.
For the study, published in the journal OncoImmunology, the team analysed data from 195 metastatic melanoma patients who were treated with immunotherapy.
They compared survival between the patients taking beta 1-selective blockers, pan beta blockers and no beta blockers and found that patients taking pan beta blockers lived significantly longer than the others.
Five years after immunotherapy, about 70 per cent of patients receiving pan beta blockers were still alive, versus about 25 per cent of those taking beta 1-selective blockers or no beta blockers at all.
In a follow-up experiment with mice, the researchers saw the same results.
The results suggest that reducing physiological stress with beta blockers can help improve the effectiveness of immunotherapy and survival for melanoma patients.
- Triple Patch Procedure saves life of 11-years old Nanded Boy who suffered from rare heart Disease – Suprovalvar Aortic Stenosis - June 19, 2019
- India Healthcare IT Market Outlook to 2023 - June 18, 2019
- 11% of Individuals suffer from Depression Disorder in Maharashtra - June 18, 2019
- Father’s Day: Helping fathers fight back pain - June 17, 2019
- Tips to survive the summers better by Mr Satkam Divya, CEO, KlinicApp - June 12, 2019
- बजाज फिनसर्व अपने #FitForLife अभियान के साथ स्वस्थ भारत की परिकल्पना को करेगा साकार - June 12, 2019
- India to give Cancer Treatment Technology to the West - June 8, 2019
- खाने के बर्तनों का साइज छोटा करके भी हो सकता है डाइट कंट्रोल : जानी-मानी डाइटिशियन स्नेहा परांजपे का सेमिनार - June 6, 2019
- Aster CMI Hospital showcases its commitment towards environment conservation - June 5, 2019
- Aster CMI Hospital gives new lease of life to an 8-year-old rural kid through affordable liver transplant initiative - June 3, 2019