Adults who have received a double vaccination are 49% less likely to have Long COVID should they contract a COVID-19 infection.
Researchers at King’s College London analyzed data from participants logging their symptoms, tests and vaccines on the UK ZOE COVID Symptom Study app between 8th December 2020 and 4 July 2021, including 1,240,009 (first dose) and 971,504 (second dose) vaccinated UK adults. The research team assessed a range of factors, including age, frailty and areas of deprivation and compared that with post-vaccination infection.
The study, published today in the Lancet Infectious Diseases, found that in the unlikely event of catching COVID-19 after being double vaccinated, the risk of Long COVID was reduced by almost half. There were also fewer hospitalisations (73% less likely) and lower burden of acute symptoms (31% less likely) among those fully vaccinated. The nature of the most common symptoms were similar to unvaccinated adults – e.g. anosmia,(loss of smell) cough, fever, headaches, and fatigue. All these symptoms were milder and less frequently reported by people who were vaccinated, and they were half as likely to get multiple symptoms in the first week of illness. Sneezing was the only symptom which was more commonly reported in vaccinated people with COVID-19.
More than 1.2 million and 0.9 million entries were made on the application by individuals who were vaccinated with the single dose and double dose respectively during the period and formed the core database for the researchers’ analysis. Apart from highlighting the efficacy of single and double dose vaccination on the individuals, the research also gave other insights about the pandemic including symptoms, existing morbidities among others. Significantly the researchers found that individuals who contract the virus despite vaccination exhibit similar symptoms to that manifested in patients who contract the disease prior to their vaccination. The researchers also said that individuals residing in deprived areas were more at risk of contracting the disease post vaccination.
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