What is the dosage for Ketalar?
Important Dosage And Administration Information
Ketalar should be administered by or under the direction of physicians experienced in the administration of general anesthetics, maintenance of a patent airway, and oxygenation and ventilation. Continuously monitor vital signs in patients receiving Ketalar.
Emergency airway equipment must be immediately available.
Do not administer the 100 mg/mL concentration of Ketalar intravenously without proper dilution. Must be used immediately after dilution.
While some degree of airway protection may be afforded due to active laryngeal-pharyngeal reflexes, vomiting and aspiration may occur with Ketalar. Ketalar is not recommended for use in patients who have not followed nil per os guidelines.
Recommended Dosage And Administration
The Ketalar dosage must be individualized and titrated to the desired clinical effect.
If a longer duration of effect is desired, additional increments can be administered intravenously or intramuscularly to maintain anesthesia. However, a higher total dose will result in a longer time to complete recovery.
Induction Of Anesthesia
The initial dose of Ketalar administered intravenously may range from 1 mg/kg to 4.5 mg/kg. The average amount required to produce 5 to 10 minutes of surgical anesthesia within 30 seconds following injection is 2 mg/kg. Administer Ketalar slowly (i.e., over a period of 60 seconds). Rapid administration may result in respiratory depression and enhanced vasopressor response. The induction dose may be administered as an intravenous infusion at a rate of 0.5 mg/kg/min.
The initial dose of Ketalar administered intramuscularly may range from 6.5 to 13 mg/kg. A dose of 9 to 13 mg/kg usually produces surgical anesthesia within 3 to 4 minutes following injection, with the anesthetic effect usually lasting 12 to 25 minutes. Administer a benzodiazepine, if clinically indicated, for the prevention of neuropsychological manifestations during emergence from anesthesia.
Maintenance Of Anesthesia
Adjust the maintenance dose according to the patient’s anesthetic needs and whether an additional anesthetic agent is administered.
Repeat increments of one-half to the full induction dose as needed for maintenance of anesthesia. Purposeless and tonic-clonic movements of extremities may occur during the course of ketamine anesthesia. These movements do not imply a light plane and are not indicative of the need for additional doses of the anesthetic.
Ketalar given by slow microdrip infusion technique at a dose of 0.1 to 0.5 mg/minute will maintain general anesthesia in adult patients induced with Ketalar. Augment Ketalar with an intravenous benzodiazepine for the prevention of neuropsychological manifestations during emergence.
Supplement To Other Anesthetic Agents
Ketalar can be administered to supplement other general and local anesthetic agents. Continuously monitor patients for changes in respiratory and hemodynamic parameters.
A reduced dose of Ketalar can be used to produce balanced anesthesia when used in combination with other anesthetic agents.
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