The Asian tiger mosquito does not pose a major risk for Zika virus epidemics, according to a study published December 31 in the open-access journal PLOS Pathogens by Albin Fontaine of the Institut de Recherche Biomédicale des Armées, and colleagues.
Zika virus has triggered large outbreaks in human populations, in some cases causing congenital deformities, fetal loss, or neurological problems in adults. While the yellow fever mosquito Aedes aegypti is considered the primary vector of Zika virus, the Asian tiger mosquito Aedes albopictus has been shown experimentally to transmit the virus and was involved in several transmissions of the virus in France in 2019. Originating from Southeast Asia, Ae. aegypti is an aggressive biter that has invaded the world and is now present on all inhabited continents, including temperate Europe, due to its ability to endure harsh winter conditions. As the second most important vector of human viral pathogens, Ae. albopictus is displacing Ae. aegypti populations due to competitive advantages. But it is not known if Ae. albopictus could trigger large-scale Zika virus epidemics.
To address this question, the researchers exposed Ae. albopictus to Zika virus and assessed infection rates in experiments, modeled the dynamics of Zika virus infection within individual humans, and used epidemiological simulations. The highest risk of transmission occurred during the pre-symptomatic stage of the disease. At this dose, mosquito infection probability was estimated to be 20%, and 21 days were required to reach median systemic infection rates. Despite these unfavorable characteristics for transmission, Ae. albopictus was still able to trigger large outbreaks in a simulated environment in the presence of sufficiently high mosquito densities and biting rates. According to the authors, active surveillance and eradication programs should be implemented in territories occupied by Ae. albopictus to maintain the low risk of Zika virus outbreaks.
The authors conclude, “The complementary combination of dose-dependent experimental infection, modeling of intra-human viremia dynamics, and in silico epidemiological simulations confirms the low epidemic potential of Aedes albopictus for Zika virus.”
Greater mosquito susceptibility to Zika virus fueled the epidemic
Lequime S, Dehecq J-S, Matheus S, de Laval F, Almeras L, Briolant S, et al. (2020) Modeling intra-mosquito dynamics of Zika virus and its dose-dependence confirms the low epidemic potential of Aedes albopictus. PLoS Pathog 16(12): e1009068.
Asian tiger mosquito poses low risk for Zika virus outbreaks (2020, December 31)
retrieved 31 December 2020
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.
- Ayush Ministry signs MoU with Ministry of Rural Development to empower the rural youth - March 17, 2023
- Know what’s best for your ‘Kidney’ – Understand the ‘Y.’ - March 9, 2023
- KidneyHealthForAll on World Kidney Day - March 9, 2023
- COVID case rates hit new high for England, study finds - April 7, 2022
- Govt’s focus on affordable healthcare ensured significant savings for poor, middle class: PM Modi - April 7, 2022
- SRL Diagnostics and Skye Air Mobility collaborate to transport pathology samples using drone logistics - April 6, 2022
- Healthineers sets up new production line of CT scanners in Bengaluru under PLI scheme - April 6, 2022
- Lupin inks licensing pact with Alvion to market drugs in Southeast Asia - April 6, 2022
- Yoga Mahotsav: Ayush Ministry to organise event to demonstrate common yoga on World Health Day - April 6, 2022
- LordsMed forays into the medtech space with launch of health ATMs ‘Lords Sehat’ - April 5, 2022