Leiomyosarcoma (LMS) is a malignant tumor that originates in smooth muscle cells. Leiomyosarcoma (LMS) is not hereditary, which means it does not run in families. However, LMS can be part of many genetic syndromes that can be inherited.
Leiomyosarcoma (LMS) is not hereditary, which means it does not run in families. However, LMS can be part of many genetic syndromes that can be inherited. So, the doctor may screen a person for inherited genetic syndromes if their family member has one of the syndromes or if the person is showing symptoms.
The following syndromes increase the risk of leiomyosarcoma
What is leiomyosarcoma?
Leiomyosarcoma (LMS) is a malignant tumor that originates in smooth muscle cells. It is a rare and aggressive type of cancer that tends to grow fast if not diagnosed in time.
Before learning about LMS, it is important to learn about smooth muscles. There are two types of muscles in the body: voluntary and involuntary. Involuntary muscles do not contract voluntarily. They control our involuntary functions, such as breathing, digestion and blood pressure. Smooth muscles react involuntarily in response to various stimuli. Some functions of smooth muscles at different locations include
- Smooth muscles that line the walls of the digestive tract help peristalsis, which helps to transport food.
- Smooth muscles in the skin cause goosebumps to form in response to cold.
- Smooth muscles in the salivary glands cause them to secrete saliva in response to taking a bite of food.
Smooth muscles are found almost everywhere in the body. Hence, LMS can form almost anywhere, including
- Blood vessels
- Genitourinary system
- Gastrointestinal tract
- Retroperitoneum (the space behind the abdominal cavity)
- Uterus (the most common site of LMS)
LMS is classified under soft tissue sarcoma. Sarcomas are cancerous tumors that start from the connective tissue, which connects, supports and surrounds organs. Soft tissue includes
- Blood and lymph vessels
What are other risk factors associated with leiomyosarcoma?
Most people who get leiomyosarcoma (LMS) are over the age of 50 years old. Other risk factors associated with LMS include
Other causes of LMS include
Are there any early screening tests that can be done for LMS?
Currently, there aren’t any targeted screening tests for leiomyosarcoma (LMS). The only way to prevent LMS is to limit exposure to the risk factors. However, even people without any risk factors can develop LMS, so at this time there is no known way to prevent LMS.
How is LMS diagnosed?
If a person has signs and symptoms of LMS, the physician may probably recommend these tests to identify LMS
- Medical history and physical examination
- Imaging tests, such as plain X-ray, computed tomography (CT) scans, magnetic resonance imaging (MRI), ultrasound and positron emission tomography (PET) scan
Medically Reviewed on 4/9/2021
American Cancer Society
National Organization for Rare Disorders
Genetic and Rare Diseases Information Center
- WHO’s technical advisory group to meet on Oct 26 to consider Covaxin - October 19, 2021
- 163 oxygen plants set up in MP after shortage during 2nd COVID-19 wave: CM Shivraj Singh Chouhan - October 19, 2021
- India’s R-value below 1 since September, researchers say - October 19, 2021
- Mumbai: Double vaccine jab not mandatory to enter theatres, colleges to reopen with 50% attendance - October 19, 2021
- Daily exercise routine, balanced diet, active lifestyle & quality sleep key to success in personal & professional lives: Experts - October 19, 2021
- Storia® Food & Beverages gets backed by Sixth Sense Ventures - October 19, 2021
- No COVID-19 death in Mumbai for first time almost since pandemic began - October 18, 2021
- New govt hospital to come up in Delhi’s Shalimar Bagh - October 18, 2021
- Mix-and-match vaccines highly effective against COVID-19: Lancet - October 18, 2021
- Self-reliance: Govt aims to make semiconductors in India by mid-2022 - October 18, 2021