The above mentioned reasons explain why Vitamin D is equally important in men as it is for women. Experts from the University of Manchester suggest that low level of Vitamin D in middle-aged men may lead to loss of strength and muscle mass. It can also lead to frailty wherein a man may feel a gradual dip in energy levels and physical capacity. Men with low Vitamin D, and insulin-like growth factor -1 (IGF-1) and its binding protein 3 (IGFBP3) were more prone to frailty.
Men who have low levels of muscle and bone building hormone were also found to be more susceptible to frailty. Older men with low levels of the hormone dehydroepiandrosterone sulfate (DHEA-S) were also linked to a higher likelihood of worsening frailty. DHEA-S has a direct anabolic effect on muscle mass.
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